The invention discloses a synthesis meth...
The present invention provides a method ...
The invention provides a 3-oxetanone syn...
The invention discloses a preparation me...
oxetan-3-ol
oxetan-3-one
Conditions | Yield |
---|---|
With
phosphorus pentoxide; triethylamine;
In
dichloromethane; dimethyl sulfoxide;
at 10 - 40 ℃;
for 2h;
Solvent;
Reagent/catalyst;
|
65.3% |
With
phosphorus pentoxide; dimethyl sulfoxide; triethylamine;
In
dichloromethane;
at -5 - 5 ℃;
|
48% |
With
pyridine; chromium(VI) oxide;
In
dichloromethane;
at 5 - 20 ℃;
|
|
With
phosphorus pentoxide; dimethyl sulfoxide; triethylamine;
In
dichloromethane;
Large scale;
Industrial scale;
|
|
With
9-azabicyclo<3.3.1>nonane-N-oxyl; oxygen; acetic acid; sodium nitrite;
at 20 ℃;
for 2h;
under 760.051 Torr;
Reagent/catalyst;
Solvent;
|
93 %Spectr. |
With
N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutylammomium bromide; sodium hydrogencarbonate;
In
dichloromethane;
at 30 - 40 ℃;
for 2h;
Reagent/catalyst;
|
49.0 g |
3-chloro-2-oxopropyl-2-bromobenzoate
oxetan-3-one
Conditions | Yield |
---|---|
With
potassium hydroxide;
In
methanol;
at 80 ℃;
for 8h;
Solvent;
Temperature;
Reagent/catalyst;
|
72% |
diazomethane
chloroacetyl chloride
3,3-dimethoxyoxetane
oxetan-3-ol
(4-chloro-phenyl)-oxetan-3-yl-amine
4-(3-hydroxyoxetan-3-yl)benzenecarbonitrile
ethyl 2-(oxetan-3-ylidene)acetate
3-[6-(5-Methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridin-3-yl]-oxetan-3-ol