1985607-83-7

7,8-Difluoro-6,11-dihydro-dibenzo[b,e]thiepin-11-ol

7,8-Difluoro-6,11-dihydro-dibenzo[b,e]thiepin-11-ol

Another Name:
CasNo.: 1985607-83-7
MF:
MW: 264.296
Storage:
Online consultation
ch_Name: 7,8-Difluoro-6,11-dihydro-dibenzo[b,e]thiepin-11-ol
English name: 7,8-Difluoro-6,11-dihydro-dibenzo[b,e]thiepin-11-ol
CasNo.: 1985607-83-7
MF:
MW: 264.296

Buy Good Quality 7,8-Difluoro-6,11-dihydro-dibenzo[b,e]thiepin-11-ol 1985607-83-7 with a minimum purity of 99%

  • Molecular Formula:C14H10F2OS
  • Molecular Weight:264.296
  • Boiling Point:379.5±42.0 °C(Predicted) 
  • PKA:12.57±0.20(Predicted) 
  • Density:1.400±0.06 g/cm3(Predicted) 

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1985607-83-7 Process route

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one
2136287-66-4

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol
1985607-83-7

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol

Conditions
Conditions Yield
With sodium tetrahydroborate; In ethanol; at 20 - 50 ℃; for 5h; Solvent; Large scale;
98%
With sodium tetrahydroborate; sodium hydroxide; In water; isopropyl alcohol; at 40 ℃; for 1.5h;
97%
With sodium tetrahydroborate; In ethanol; water; Cooling with ice;
97%
With sodium tetrahydroborate; sodium hydroxide; In isopropyl alcohol; at 40 ℃; for 2h;
97%
With sodium tetrahydroborate; water; sodium hydroxide; In isopropyl alcohol; at 0 - 40 ℃;
97%
With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 0.333333h;
97.7%
With sodium tetrahydroborate; sodium hydroxide; In water; isopropyl alcohol; at 40 ℃; for 1.5h;
97%
With sodium tetrahydroborate; sodium hydroxide; In isopropyl alcohol; at 40 ℃; for 4h; Cooling with ice;
95%
With sodium tetrahydroborate; In isopropyl alcohol; at 10 - 55 ℃; Solvent; Temperature;
94.7%
With sodium tetrahydroborate; In methanol; at -10 - 20 ℃; for 4h;
93.2%
With methanol; sodium tetrahydroborate; at -5 - 20 ℃; for 5h;
91.5%
With methanol; sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 1h;
With sodium tetrahydroborate; In isopropyl alcohol; at 40 ℃; for 1h;
1.8 g
7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one
2136287-66-4

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol
1985607-83-7

7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepine-11-ol

Conditions
Conditions Yield
With borane-THF; (S)-5,5-diphenyl-2-methoxy-3,4-propano-1,3,2-oxazaborolidine; In toluene; at 20 - 30 ℃; for 1.5h; Reagent/catalyst; Solvent; Temperature; enantioselective reaction; Inert atmosphere;
93.7%
With EBSDR8; isopropyl alcohol; NADH; In aq. phosphate buffer; at 30 - 35 ℃; pH=7.2 - 7.5; Enzymatic reaction;
91%
With formic acid; RuCl(p-cymene)[(R,R)-Ts-DPEN]; triethylamine; In tetrahydrofuran; at 60 - 70 ℃; Inert atmosphere;
98.62 % ee

1985607-83-7 Upstream products

  • 455-86-7
    455-86-7

    3,4-Difluorobenzoic acid

  • 2136287-65-3
    2136287-65-3

    3,4-difluoro-2-((phenylthio)methyl)benzoic acid

  • 2136287-66-4
    2136287-66-4

    7,8-difluoro-6,11-dihydrodibenzo[b,e]thiazepin-11-one

  • 930-69-8
    930-69-8

    sodium thiophenolate

1985607-83-7 Downstream products

  • 1985605-59-1
    1985605-59-1

    (R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

No data available
No data available